Press Release - No. 14/2018
Zealand Pharma to present new clinical Phase 2 results on glepaglutide for the treatment of short bowel syndrome at the DDW conference in the U.S.
Copenhagen, May 31, 2018 - Zealand Pharma ("Zealand"), announces that Rahim M. Naimi, MD and Mark Hvistendahl, MSc in clinical nutrition, both Department of Gastroenterology, Rigshospitalet, University of Copenhagen, Denmark, will present new results from the Phase 2 trial for the treatment of short bowel syndrome at the annual Digestive Disease Week (DDW) meeting June 2-5, 2018 in Washington, DC, U.S. The abstracts has been published on the DDW website.
The DDW conference is the world's largest gathering of medical professionals in the specialties of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. The three abstracts are:
Poster presentation session on June 3rd, 2018 (Abstract No. 2897919)
Oral presentation on June 4th, 2018 (Abstract No. 2904756)
Oral presentation on June 5th, 2018 (Abstract No. 2888499)
Adam Steensberg, Executive President and Chief Medical and Development Officer of Zealand comments: "We are very pleased with the comprehensive results from the glepaglutide Phase 2 trial and the progress towards offering patients with short bowel syndrome a new potential once-weekly convenient treatment opportunity. The new clinical Phase 2 results presented at the DDW conference are encouraging, and we look forward to soon start the Phase 3 confirmatory trial."
The Phase 2 trial was conducted in collaboration with investigator Prof. Palle B Jeppesen and team at
Rigshospitalet, University of Copenhagen, Denmark, one of the world's leading centers for the treatment of SBS. The trial was a 3-week proof-of-concept, double-blind, cross-over, dose-finding trial investigating the efficacy and safety of three different doses of glepaglutide (0.1 mg, 1 mg and 10 mg per day). Following, positive End-of-Phase 2 interactions with the US FDA and EU EMA, Zealand remains on track for initiating the pivotal Phase 3 trial in H2 2018. The 26-week trial will enroll approximately 130 patients with short bowel syndrome to test efficacy and safety of once- and twice weekly dosing with glepaglutide over placebo.
For further information, please contact:
Britt Meelby Jensen, President and CEO
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About Zealand Pharma A/S
Zealand Pharma A/S (Nasdaq Copenhagen and New York: ZEAL) ("Zealand") is a biotechnology company focused on the discovery, design and development of innovative peptide-based medicines. Zealand has a late-stage clinical portfolio of proprietary product candidates focusing on specialty gastrointestinal and metabolic diseases. In addition, it has two marketed products, commercialized by Sanofi, and two product candidates under license collaboration with Boehringer Ingelheim.
Zealand is based in Copenhagen (Glostrup), Denmark. For further information about the Company's business and activities, please visit www.zealandpharma.com or follow Zealand on LinkedIn or Twitter @ZealandPharma.